{"id":2005,"date":"2026-09-02T07:57:05","date_gmt":"2026-09-02T07:57:05","guid":{"rendered":"https:\/\/www.skinandme.com\/info\/?page_id=2005"},"modified":"2026-09-02T13:16:42","modified_gmt":"2026-09-02T13:16:42","slug":"the-tretinoin-patient-information-leaflet","status":"publish","type":"page","link":"https:\/\/www.skinandme.com\/info\/support\/patient-information-leaflets\/the-tretinoin-patient-information-leaflet\/","title":{"rendered":"The Tretinoin Patient Information Leaflet &#8211; Skin+Me Essentials"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">This document contains important information about using your treatment. Before you apply<br>your first dose, please read all of the following information.<br>This documents refers to the following topical preparations:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Tretinoin 0.006% serum<\/li>\n\n\n\n<li>Tretinoin 0.012% serum<\/li>\n\n\n\n<li>Tretinoin 0.024% serum<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">In this Information Leaflet, you\u2019ll find:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>General treatment information<\/li>\n\n\n\n<li>Contraindications<\/li>\n\n\n\n<li>Information about your active ingredients and the base serum<\/li>\n\n\n\n<li>Storage instructions and guidance<\/li>\n\n\n\n<li>How to report side effects<\/li>\n<\/ol>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">1. General treatment information<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Your Skin + Me Essentials tube contains approximately 8ml of serum compounded by The<br>Feel Good Pharmacy, Unit 5 Oakwood Business Park, Standard Road, London, NW10 6EX.<br>The treatment has been prescribed for your skin, and only your skin. Please don\u2019t share this<br>treatment with anyone else, as it may cause harm<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Application + Usage<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u25cf Your treatment is only ever for <strong>external<\/strong> use.<br>\u25cf Wash hands before and after you apply your treatment.<br>\u25cf Wash your face, and allow your skin to completely dry.<br>\u25cf One dose is to be used <strong>once a day<\/strong>, at night time. Gently squeeze 5.5cm<br>(approximately 0.28ml) of serum onto a clean finger. Use the measuring guide<br>provided in your Daily Serum pack to measure out the recommended dose.<br>\u25cf Do not use more treatment than prescribed, or more often or for longer than<br>instructed. Doing so can increase your chances of experiencing side effects.<br>\u25cf Apply a thin layer of the serum to your whole face, avoiding the immediate eye area<br>and mouth.<strong> Do not apply to any areas of broken skin.<\/strong><br>\u25cf Do not swallow your serum.<br>\u25cf If you miss a dose, just apply the following evening. Don\u2019t double up on applications.<br>\u25cf It can take several weeks before you see initial improvements in your skin. The<br>prescribed treatment plan should be followed as directed by your Prescriber.<br>\u25cf Do not use your serum past the expiry date printed on the label of your treatment.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">2. Contraindications<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Treatments containing Tretinoin should NOT be used if you are pregnant,<br>breastfeeding or trying to conceive<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Do not use your treatment if you have a known allergy to any of the active ingredients or to<br>the base serum (see section 3).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>If you develop an allergic reaction to your treatment then you must stop applying it. For your<br>reference, signs of an allergic reaction may include rash; hives; itching; shortness of breath;<br>wheezing; cough; swelling of the face, lips, tongue or throat.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>If in doubt, do not hesitate to ask your doctor or pharmacist for advice and call 999 in a<br>medical emergency.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">3. Information about your active ingredients and the base serum<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">3a. Tretinoin &#8211; warnings and precautions<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><strong>Side effects: <\/strong>There may be a brief initial sensation of warmth or stinging immediately after<br>applying this medication. Local side effects such as dry skin, redness, itching, rashes,<br>irritation and mild peeling are common (seen in between one in 10 and one in 100 users).<br>These effects tend to settle with time. There is also a small chance of an initial flare of acne<br>and its associated complications including scarring. More severe side effects such as<br>swelling, blisters, skin burning sensation, eye irritation, skin discolouration, crusting and<br>significant skin peeling may occur uncommonly (seen in between one in 100 and one in<br>1000 users). Rarely skin hyperpigmentation (darkening of the skin) and hypopigmentation<br>(lightening of the skin) and severe allergic reactions can occur (seen in between one in 1000<br>and one in 10, 000 users).<br>There have been 3 case reports of topical Tretinoin being associated with the development<br>of Idiopathic Intracranial Hypertension. There is no evidence proving it can cause it but if you<br>have this condition you may not want this treatment and you should stop treatment and<br>speak to your GP or healthcare provider if you do develop any symptoms. If you experience<br>any of these more serious skin reactions please stop treatment and contact us for further<br>advice, or speak to your GP or healthcare provider.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><strong>Do not use if your skin is sunburned.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>You may find that your skin is more sensitive to sunlight and sunburns more easily with<br>Tretinoin use. An appropriate sunscreen (minimum SPF 30 with UVA and UVB protection)<br>and\/or protective clothing should be used daily whenever applying tretinoin. Avoid using<br>sunbeds, tanning lamps and strong sun.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Avoid using exfoliating products, soaps\/cleaners with a strong drying effect, alcohol products<br>and scented facial products as this may further irritate your skin. Avoid waxing whilst using<br>this treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>WARNING: TRETINOIN MAY CAUSE HARM TO AN UNBORN BABY IF USED WHILE<br>PREGNANT. IF YOU ARE PREGNANT, BECOME PREGNANT OR ARE PLANNING A<br>PREGNANCY WHILST USING THIS MEDICATION OR WITHIN ONE MONTH AFTER<br>STOPPING TREATMENT, PLEASE CONTACT YOUR DOCTOR. PLEASE ENSURE<br>ADEQUATE CONTRACEPTION IS TAKEN WHILST USING THIS MEDICATION AND<br>STOP ONE MONTH BEFORE TRYING TO CONCEIVE.<\/strong><\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Our base serum<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Base serum ingredients: Aqua, Propylene Glycol, Ethanol, Isopropyl palmitate, Dimethicone,<br>Glycerin, Ectoin, Polyacrylate Crosspolymer-6, Polysorbate 80, Polysilicone-11,<br>Ethylhexylglycerin, Butylene Glycol, Phenoxyethanol, Disodium EDTA, Butylated<br>hydroxytoluene (BHT), Decyl Glucoside, Hexylene Glycol and Caprylyl Glycol.<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">4. Storage instructions and guidance<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>KEEP THIS MEDICATION OUT OF SIGHT AND REACH OF CHILDREN.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Do not flush unused medication or pour it down the sink, and do not place it in the general<br>waste bin. Please ask your pharmacist what to do with unused medication. These measures<br>are in place to help the environment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>Store in a cool dry place below 25-degree Celsius and out of direct sunlight.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>Do not use your medication after the expiry date which is shown on the packaging<\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">5. How to report side effects<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you experience any unwanted side effects, you should contact us via the Dermatology<br>Support team or talk to your GP or healthcare professional. Also, you can help to make sure<br>medicines remain as safe as possible for everyone by reporting any unwanted side effects<br>directly via <a href=\"http:\/\/www.mhra.gov.uk\/yellowcard\">www.mhra.gov.uk\/yellowcard<\/a> or search for MHRA Yellow Card in the Google Play<br>or Apple App Store.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>Last update: 27\/08\/2026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This document contains important information about using your treatment. Before you applyyour first dose, please read all of the following information.This documents refers to the following topical preparations: In this Information Leaflet, you\u2019ll find: 1. General treatment information Your Skin + Me Essentials tube contains approximately 8ml of serum compounded by TheFeel Good Pharmacy, Unit [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":0,"parent":148,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2005","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/pages\/2005","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/comments?post=2005"}],"version-history":[{"count":2,"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/pages\/2005\/revisions"}],"predecessor-version":[{"id":2016,"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/pages\/2005\/revisions\/2016"}],"up":[{"embeddable":true,"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/pages\/148"}],"wp:attachment":[{"href":"https:\/\/www.skinandme.com\/info\/wp-json\/wp\/v2\/media?parent=2005"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}