{"id":1558,"date":"2023-07-13T08:00:00","date_gmt":"2023-07-13T07:00:00","guid":{"rendered":"https:\/\/www.skinandme.com\/the-dose\/?p=1558"},"modified":"2024-02-16T11:32:04","modified_gmt":"2024-02-16T11:32:04","slug":"ingredient-deep-dive-hydroquinone","status":"publish","type":"post","link":"https:\/\/www.skinandme.com\/the-dose\/ingredient-deep-dive-hydroquinone\/","title":{"rendered":"Ingredient Deep Dive: Hydroquinone"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.skinandme.com\/the-dose\/wp-content\/uploads\/2021\/10\/Copy-of-Skin-Me-Ingredient-Deep-Dive-Hydroquinone-1024x683.jpg\" alt=\"\" class=\"wp-image-1561\"\/><\/figure>\n\n\n\n<h1 class=\"has-medium-font-size wp-block-heading\"><strong>Ingredient Deep Dive: Hydroquinone<\/strong><\/h1>\n\n\n\n<p>Do you have hydroquinone on your skincare radar? Used by dermatologists to treat <a href=\"https:\/\/www.skinandme.com\/the-dose\/ask-a-dermatologist-what-is-hyperpigmentation\/\">hyperpigmentation<\/a>, there are many myths surrounding this ingredient.&nbsp;<\/p>\n\n\n\n<p>Today we\u2019ll take a closer look at what hydroquinone actually is, how it treats hyperpigmentation, how you should use it, possible side effects and any other bits of juicy info you need to know.<\/p>\n\n\n\n<h2 class=\"has-medium-font-size wp-block-heading\"><strong>What is hydroquinone?<\/strong><\/h2>\n\n\n\n<p>Hydroquinone is a prescription-only ingredient which lightens the skin. Dermatologists may prescribe it in cases of hyperpigmentation, which is when darker patches appear on the skin as a result of inflammation, sun damage or <a href=\"https:\/\/www.skinandme.com\/the-dose\/melasma-101\/\" data-type=\"post\" data-id=\"1549\">melasma<\/a>.<\/p>\n\n\n\n<p>Hydroquinone was first created in 1820, but in-depth research on the ingredient took off in the 1940s. Since then, scientists experimented with different strengths of hydroquinone and investigated its potential uses in skincare<\/p>\n\n\n\n<p>Historically, it\u2019s been a controversial ingredient due to its potential for misuse as a way to make large areas of dark skin look paler. However, in the UK it cannot be bought over the counter and is only prescribed to treat chronic skin conditions which may impact an individual\u2019s confidence and self esteem.<\/p>\n\n\n\n<h2 class=\"has-medium-font-size wp-block-heading\"><strong>How does hydroquinone treat hyperpigmentation?<\/strong><\/h2>\n\n\n\n<p>Our skin\u2019s natural colour is determined by a pigment called melanin which is produced by cells in the top layer of our skin, called the epidermis. <a href=\"https:\/\/www.skinandme.com\/the-dose\/ask-a-dermatologist-what-is-hyperpigmentation\/\">Hyperpigmentation<\/a> most commonly occurs when melanin is overproduced, which leads to dark spots or patches on the skin\u2019s surface. Post-inflammatory hyperpigmentation (or PIH), solar lentigos and <a href=\"https:\/\/www.skinandme.com\/the-dose\/melasma-101\/\" data-type=\"post\" data-id=\"1549\">melasma<\/a> are three of the most common types of hyperpigmentation.&nbsp;<\/p>\n\n\n\n<p>PIH occurs when the skin\u2019s melanin-producing cells overproduce the pigment in response to inflammation, for example following a bout of <a href=\"https:\/\/www.skinandme.com\/the-dose\/the-skin-and-me-guide-to-acne\/\" data-type=\"post\" data-id=\"467\">acne<\/a>. Solar lentigos is the medical name for the dark, flat patches that appear following chronic sun exposure \u2013 sometimes they are called age spots, sun spots or liver spots.&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p>Melasma is a common skin condition characterised by flat, usually symmetrical, darker areas of the skin. It is common during <a href=\"https:\/\/www.skinandme.com\/the-dose\/a-dermatologists-guide-to-pregnancy-safe-skincare\/\" data-type=\"post\" data-id=\"1045\">pregnancy<\/a> and is thought to be linked to hormonal changes. Sun exposure also plays a role in melasma, as dermatology clinics tend to see more people with the condition in Autumn, after the warmer months.&nbsp;<\/p>\n\n\n\n<p>The gold standard treatment for melasma is a \u2018triple therapy\u2019 consisting of hydroquinone, <a href=\"https:\/\/www.skinandme.com\/the-dose\/tretinoin-101\/\" data-type=\"post\" data-id=\"3530\">tretinoin<\/a> and hydrocortisone. Hydroquinone works to lighten the darker patches while tretinoin, a retinoid 20 times stronger than <a href=\"https:\/\/www.skinandme.com\/the-dose\/active-ingredients-whats-better-than-retinol\/\" data-type=\"post\" data-id=\"3819\">retinol<\/a>, increases cell turnover. Hydrocortisone, a mild steroid, soothes any inflammation or irritation caused by these powerful ingredients. This combination has been found to be a more effective treatment for hyperpigmentation than using these ingredients alone.&nbsp;<\/p>\n\n\n\n<p>Here\u2019s the science-y bit. Usually melanocytes (melanin-producing cells) convert tyrosine (an amino acid) into melanin with the help of an enzyme called tyrosinase. In cases of hyperpigmentation, the cells produce more melanin than usual. Hydroquinone works by inhibiting tyrosinase, temporarily reducing the production of melanin.&nbsp;<\/p>\n\n\n\n<h2 class=\"has-medium-font-size wp-block-heading\"><strong>How do you use hydroquinone?<\/strong><\/h2>\n\n\n\n<p>You should only use hydroquinone if it has been prescribed to you, and you should only use it exactly as directed by your clinician.&nbsp;<\/p>\n\n\n\n<p><strong>Top tip #1:<\/strong> If you\u2019re using a treatment cream that contains hydroquinone, you should apply it after cleansing but before moisturising. Massage a small amount of the product into your skin until completely absorbed and make sure you wash your hands after use. You don\u2019t want the powerful product ending up anywhere else and affecting other areas of the skin.&nbsp;<\/p>\n\n\n\n<p><strong>Top tip #2: <\/strong>Always wear <a href=\"https:\/\/www.skinandme.com\/the-dose\/meet-skin-and-me-daily-defence-sunscreen-spf-50\/\" data-type=\"post\" data-id=\"4587\">sunscreen<\/a> if you\u2019re using hydroquinone. Not only can the sun\u2019s rays make hyperpigmentation worse \u2013 especially solar lentigos \u2013 but it can also actually reverse the effects of the treatment.&nbsp;Why not <a href=\"https:\/\/www.skinandme.com\/login\" data-type=\"URL\" data-id=\"https:\/\/www.skinandme.com\/login\">add a tube of Daily Defence Oil-free Sunscreen SPF 50<\/a> to your next Skin + Me box? It&#8217;s been specifically designed by Dermatologists for use with <a href=\"https:\/\/www.skinandme.com\/the-dose\/how-to-get-your-skin-used-to-active-ingredients\/\" data-type=\"post\" data-id=\"4514\">active ingredients<\/a> like hydroquinone. <\/p>\n\n\n\n<p><strong>Top tip #3:<\/strong> Make sure you avoid products containing peroxide, such as hydrogen peroxide and benzoyl peroxide, as this combination can stain the skin. Harsh ingredients such as AHAs should also be avoided when you\u2019re using hydroquinone.<\/p>\n\n\n\n<h2 class=\"has-medium-font-size wp-block-heading\"><strong>Does hydroquinone have any side effects?<\/strong><\/h2>\n\n\n\n<p>Hydroquinone can cause <a href=\"https:\/\/www.skinandme.com\/the-dose\/dry-skin-101-dry-skin-causes-symptoms-and-treatment\/\" data-type=\"post\" data-id=\"2431\">dryness<\/a> or irritation when you start using it. If you are prone to dry or sensitive skin already then caution is needed \u2013 your prescribing clinician will be able to advise you on how to use hydroquinone safely.&nbsp;<\/p>\n\n\n\n<p>Dryness and irritation often ease once the skin has fully adjusted to the new ingredients. People with more balanced or <a href=\"https:\/\/www.skinandme.com\/the-dose\/oily-skin-101-oily-skin-causes-symptoms-and-treatment\/\" data-type=\"post\" data-id=\"2606\">oily skin types<\/a> will be less likely to experience dryness or irritation.&nbsp;<\/p>\n\n\n\n<p>Ochronosis is a rare condition that results in blue, black or grey marks on the skin and can be caused by excessive use of hydroquinone. The majority of cases of ochronosis are linked to the use of very high concentration. of hydroquinone several times a day for several years. No cases of ochronosis have been reported when hydroquinone is used at concentration between two and five percent, for short periods of time under medical supervision.&nbsp;<\/p>\n\n\n\n<p>There have been reports of cancer associated with the use of hydroquinone, but it is important to point out that these were only seen in animal studies and when hydroquinone was used orally. There have been no reports of cancer in humans after topical use of hydroquinone.&nbsp;<\/p>\n\n\n\n<p>Hyperpigmentation can be a difficult condition to treat and it can look different on everybody, as we are all unique and so is our skin. Although hydroquinone may help clear areas of hyperpigmentation, this ingredient isn\u2019t appropriate for everyone so it\u2019s always good to check in with your skin and listen to it if it doesn\u2019t seem happy. Get in touch with your prescribing clinician if you have any questions or concerns about hydroquinone treatment.&nbsp;<\/p>\n\n\n\n<h2 class=\"has-medium-font-size wp-block-heading\"><strong>The take-aways<\/strong><\/h2>\n\n\n\n<p>Hydroquinone can be a safe and effective treatment for hyperpigmentation, but you should only ever use it under medical supervision. This means no long-term use and regular medical reviews to make sure that you are not at risk of side effects.&nbsp;<\/p>\n\n\n\n<p>With the right support, controlled doses of hydroquinone can help to reduce hyperpigmentation for a smooth, even skin tone.<\/p>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group has-background\" style=\"background-color:#f0f6fb\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group has-background\" style=\"background-color:#edf5f8\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group has-background\" style=\"background-color:#f0f6fb\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p><strong>New to Skin + Me? <\/strong>Get your first month of personalised skincare for \u00a34.99 with promo code DOSE \u2013 <a href=\"https:\/\/www.skinandme.com\/consultation\/sign-up\/create-account\">complete our quick consultation here<\/a>. <\/p>\n\n\n\n<p><strong>Looking for a routine refresh? <\/strong><a href=\"https:\/\/www.skinandme.com\/login?back=%2Faccount-summary%2Fmanage-upcoming-orders\">Add the Dream Routine to your Skin + Me subscription<\/a>. <\/p>\n\n\n\n<p><strong>In need of a restock? <\/strong>Head to <a href=\"https:\/\/www.skinandme.com\/shop\">The Skincare Shop<\/a> for one-off purchases of your Routine Essentials.<\/p>\n<\/div><\/div>\n<\/div><\/div>\n<\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Hydroquinone is a superstar when it comes to dealing with hyperpigmentation and more. Read on to find out everything you need to know about this ingredient.<\/p>\n","protected":false},"author":179265348,"featured_media":1561,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1942,2196,1,1967,1366],"tags":[1424,1411,1517,2105,1583,1568,1579,2331,1382,1362,1861,1423],"class_list":["post-1558","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-guides","category-ingredients","category-latest-articles","category-pigmentation","category-routine","tag-active-ingredients","tag-dermatologist","tag-expert-advice","tag-hydrocortisone","tag-hydroquinone","tag-hyperpigmentation","tag-melasma","tag-post-inflammatory-hyperpigmentation","tag-skin-me","tag-skincare","tag-sun-damage","tag-tretinoin"],"_links":{"self":[{"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/posts\/1558","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/users\/179265348"}],"replies":[{"embeddable":true,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/comments?post=1558"}],"version-history":[{"count":14,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/posts\/1558\/revisions"}],"predecessor-version":[{"id":5945,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/posts\/1558\/revisions\/5945"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/media\/1561"}],"wp:attachment":[{"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/media?parent=1558"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/categories?post=1558"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.skinandme.com\/the-dose\/wp-json\/wp\/v2\/tags?post=1558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}